Never heard of the inside of the bed falling apart. It will show some wear. Some members with heavy usage have replaced the separate bed floor mat but it is part of the "water management system" so be careful of replacing that mat with an aftermarket mat. Some have also applied a bedliner such as Line-X but be careful not to plug the bed drains. Others install a Bedslide cargo device to cut down on wear and make it easier to get things out of the bed as well as preventing damage to bed mat,floor or tailgate.
You could also consider getting a BedRug carpet style cargo liner to dress up the bed area and protect it from damage and also quiet down noise from echoing and cargo banging around.