First, I have 2 - Polk/Momo 10" subs (which each comes in its own enclosure) in the bed behind the midgate. The enclosures are 'Monster'-velcro'd down, so that they are easily moved/removed if I need to reconfigure the space or just plain need MORE bed space, of course the wiring is quickly disconnectable. Each sub runs off a separate Sony 1000W amp (under the rear seats). Each circuit has a separate on/off switch mounted (with several other switches) in the overhead console. They've been installed for +/- 8-9 months.
Second, I'm no audiophile. My hearing suffers from way too many hours in pressurized airplanes while congested, younger years playing the drums (and some other 'events'). Not that I have any difficulty on a day-to-day, but I don't do high end audio. But I do from time-to-time, enjoy a good bass thump.
OK, that said...
Gigantic difference between the midgate up or down. With it up, the bass is present and more than enough for me most of the time. I really won't comment on the 'quality', but the quantity is there, in fact I frequently only run one circuit.
With the midgate down, it's bass city. As much as you can stand.
I can pretty much do the ricer-annoying-the-drivers-who-are-five-cars-away-thing; though that's not my thing, it was fun the first few days.