The problem with the Turbos is that they make there Power at High Boost levels jon.., usually at 10 lbs and above.., something the stock Heads, and gaskets could not handle..., not to mention the Pistons, and Bottom End...... To really get the advantage of the Turbos you would have to run Boost of 15 lbs, and above.., the first thing that would happen is you would start lifting the Heads, and blowing Head gaskets.., next would be the problem of pounding out, and cracking the tops of the stock pistons, and Ring lands.... The compression ratio on the stock 5.3 is far to high to run Boost above 10 p.s.i Max..., so you would really have to build an engine from scratch to handle Boost levels that high.. You could put in Forged pistons, good Rods, and Crank..., but the Heads could still never handle that kind of Boost.... At the 10/11 lbs Im running now..., Im really pushing it.., and wouldn't even consider trying to run anymore Boost.., and even as much as Ive beefed up My Drive Train.., Trans, Drive Shaft, Rear End.., its still on the ragged edge to hold up to the Power Im making now.., so you would have to install a complete new Drive Train to handle the Power..., and Twin Turbo's have a smaller power band than a supercharger..., so you would need a high stall converter, and a lot of gear to take advantage of the power that they make...., it would be a Very Expensive project..., and take a lot of Tuning to make it work right..., and in the End.., probably not worth it...... JMO